Department of Dermatology, Graduate School of Medicine, Kyusyu University, Japan. Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Bookshelf Many Americans become infected with them at an early age. These types cannot cause cold sores or genital herpes. Disseminated erythematous-papulosquamous lesions, with right laterocervical herald patch (clinical aspect on admission). (a) haematoxylineosin, original magnification 10. It could be pityriasis rosea here's how to treat it. As vaccine reactogenicity reports continue to surface, dermatologists and other health care providers should understand the landscape of the latest cutaneous reactions to guide and address patients' concerns. 2020 Jul;33(4):e13730. Khalili M, Abtahi-Naeini B, Rastegarnasab F, Afshar K. Clin Case Rep. 2022 Jul 19;10(7):e6096. Pityriasis rosea following SARS-CoV-2 vaccination: A case series. Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders. Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. For most people, it resolves without treatment. Ad Choices. In: Knoop KJ, Stack LB, Storrow AB, et al., eds. Moreover, almost all lesions faded with associated post-inflammatory hyperpigmentation (Figure 2B). Before Although the exact pathophysiologic mechanisms of PR after vaccination remain unclear, immune responses to COVID-19 vaccines and disruption of T-cell mediated control of latent infections were implicated (12, 1518). Learning points: Why covid arm and other post-vaccine rashes might actually be a 'good (2016) 30:5445. PMC -, Broccolo F, Drago F, Careddu AM, et al. Cutaneous manifestation has been reported in 0.2% of patients infected by COVID-19 in China, and 18 out of 88 patients from Italy. Epub 2020 Jun 29. I also had to stop working out and hiking for about a week, as Alexiades is right excessive perspiration worsened the itch. Cebeci Kahraman F, Sava Erdoan S, Akta ND, Albayrak H, Trkmen D, Borlu M, Arca DA, Demirba A, Akbayrak A, Polat Ekinci A, Gkek GE, elik HA, Taolar MK, An , Temiz SA, Hazinedar E, Ayhan E, Hzl P, Solak E, Kl A, Ylmaz E. J Cosmet Dermatol. Coronavirus: Five skin conditions linked to COVID-19 after - 9News 78 PDF Pityriasis rosea following CoronaVac COVID19 vaccination: a case report Elin Akda, N. Ilter, B. t, . Erdem Pityriasis rosea-like rash after messenger RNA COVID-19 vaccination: A case report and review of the literature. Please enable it to take advantage of the complete set of features! Cutis. doi: 10.1111/jdv.17342. An official website of the United States government. However, there isnt enough research to determine that stress may cause pityriasis rosea. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. Before Epub 2021 May 29. J Am Acad Dermatol. The transformation will take your breath away. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). It has been reported that pityriasis rosea has been triggered by several vaccines, as a rare side-effect. and transmitted securely. Washrawirul C, Triwatcharikorn J, Phannajit J, Ullman M, Susantitaphong P, Rerknimitr P. J Eur Acad Dermatol Venereol. Pityriasis rosea. Bookshelf Br J Dermatol 2021. Washrawirul C, Triwatcharikorn J, Phannajit J, Ullman M, Susantitaphong P, Rerknimitr P. J Eur Acad Dermatol Venereol. It is increasingly recognized that SARS-CoV-2 infection and COVID-19 vaccines have been associated with skin disorders, including pityriasis rosea. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). J Am Acad Dermatol. Pityriasis rosea developing after COVID19 vaccination Could covid-19 infection cause pityriasis rosea why? 2022 Mar 15;10(3):624. doi: 10.3390/microorganisms10030624. -, Polack FP, Thomas SJ, Kitchin N et al. Among 171 laboratory-confirmed COVID-19 patients with cutaneous manifestations from the registry, the most commonly reported were morbilliform rash (22 percent), pernio-like acral lesions (18 percent), urticaria (16 percent), macular erythema (13 percent), vesicular eruption (11 percent), papulosquamous eruption (9.9 percent), and retiform The .gov means its official. Would you like email updates of new search results? One week before the rash, respiratory tract infection symptomatology was observed by the patient. Yes, There Is a Correct Order for Everything You Do in the Shower, Each Zodiac Sign's Unique Personality Traits, Swoopy 1960s Hair Was Everywhere at the SAG Awards, Christina Aguilera Opened Up About Getting Injections and Why She Doesn't Care If People Judge Her, "I think we all can rely on a little help. Cutaneous Complications of mRNA and AZD1222 COVID-19 Vaccines: A Worldwide Review. Pityriasis rosea Gibert triggered by SARS-CoV-2 infection: A case Pityriasis rosea following CoronaVac COVID-19 vaccination: a case report. Drug-induced PR-like eruption accounts for 2% of all cutaneous adverse drug reactions (10). Blood tests to check for causes of a rash that arent related to pityriasis rosea. An official website of the United States government. doi: 10.1111/jdv.17498. Clin Dermatol. 2021 Sep;35 (9):e546-e548. Additional evidence that pityriasis rosea is associated with reactivation of human herpesvirus-6 and -7. Pityriasis rosea is a benign inflammatory rash that starts with a single red rash, also known as the "herald patch," which eventually gives way to a larger, similar-looking rash on the trunk. (a) Pityriasis rosea (chest, flank, and axilla); (b) pityriasis rosea (back). Luckily, it's not contagious. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. FOIA If you have pityriasis rosea, its unlikely that youll get it again. -, Welsh E, Cardenas-de la Garza JA, Cuellar-Barboza A, Franco-Marquez R, Arvizu-Rivera RI. Epub 2022 Jul 19. Federal government websites often end in .gov or .mil. Chanprapaph K, Pomsoong C, Tankunakorn J, Eden C, Suchonwanit P, Rutnin S. Comparative analyses of clinical features, histopathology, and CD123 immunohistochemistry of oral lupus erythematosus, lichen planus, and other lichenoid lesions. Dermatol Reports. Int J Infect Dis. The https:// ensures that you are connecting to the Pityriasis rosea and ringworm look similar. Bookshelf Treatment was initiated with systemic corticosteroid therapy - hydrocortisone hemisuccinate 200 mg/day for 7 days, and loratadine 10 mg 2 times a day. and transmitted securely. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The symptoms of pityriasis rosea usually develop in stages: Pityriasis rosea doesnt hurt. Foods that have anti-inflammatory properties include: Foods that may increase inflammation include: There isnt any way to prevent pityriasis rosea. Pityriasis rosea following SARS-CoV-2 vaccination: A case series. Even though it is benign, it can cause substantial. -, Drago F, Ciccarese G, Rebora A, Parodi A. Treatment with topical 0.1% triamcinolone acetonide twice daily showed partial response after seven days. eCollection 2021. 2021;185(2):e34. However, after 14 days, she developed multiple discrete blanching erythematous oval patches and plaques on the lower abdomen, back, and bilateral upper thighs (Figures 1A,B). Some treatments can alleviate related symptoms, including itching. New York City-based dermatologist Macrene Alexiades. Some people who have had cosmetic fillers used to remove . 2021;184(6):11941195. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. 2022 by the American Academy of Dermatology, Inc. See your skin clear. J Eur Acad Dermatol Venereol. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. Lawley LP, McCall CO, Lawley TJ. Pityriasis rosea developing after COVID-19 vaccination. -, Mahajan K, Relhan V, Relhan AK, et al. This reaction is self-limited and resolves in an average of 5.6 weeks. Epub 2020 Nov 20. (a) Patient 1: Thin red to tan oval plaques with peripheral scale on the trunk. Lessons: Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. sharing sensitive information, make sure youre on a federal Children often get infected when someone sneezes or kisses them. Ramot Y, Nanova K, Faitatziadou SM, Assab DA, Berkun Y, Zlotogorski A. J Dtsch Dermatol Ges. Pityriasis rosea, COVID-19 and vaccination: new keys to understand an old acquaintance. Epub 2022 Jun 21. Your Random Rash Could Be Pityriasis Rosea | Allure Sriphojanart T, Khunkhet S, Suchonwanit P. A retrospective comparative study of the efficacy and safety of two regimens of diphenylcyclopropenone in the treatment of recalcitrant alopecia areata. (2019) 34:185764. -, Broccolo F., Drago F., Careddu A.M., et al. 2021 Sep 7;8:752443. doi: 10.3389/fmed.2021.752443. Theyre both papulosquoamous (pap-you-lo-skway-miss) disorders, which is a term used to characterize skin disorders according to the presence of raised, discolored, scaly patches of skin. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. 2021;35(9):e546e548. To the best of our knowledge, there have been no reports of PR-like eruptions following inoculation with Oxford/AstraZeneca ChAdOx1 nCoV-19 (AZD1222) vaccine. Dermatol Ther. "And it has a particular [dermatomal] distribution because it's along a nerve," which also presents as fluid-filled blisters, rather than lesions. Dtsch Arztebl Int. Br J Dermatol 2020; 183: 431442. Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Int J Dermatol. Pityriasis rosea is also known as Christmas tree rash. J Med Virol 2021; 93: 18501851. 2022 Aug 11;9(8):43. doi: 10.3390/medicines9080043. Clinical aspect of the lesions after 7days of treatment. Clin Exp Dermatol 2010;35:3004. doi: 10.7759/cureus.27108. Vote for your favorite beauty products now! 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. Skin lesions appeared in a 49-year-old female 8 days after the first dose of the BNT162b2 mRNA vaccine and in a 53-year-old male 7 days after the second dose of the same . Careers. eCollection 2022. Our expert physicians and surgeons provide a full range of dermatologic, reconstructive and aesthetic treatments options at Cleveland Clinic. Med. Our reported case adds to the other findings regarding the association of PR with SARS-CoV-2 infection, in the context of the pandemic, suggesting the need to test patients with PR skin lesions for SARS-CoV-2 infection. Disclaimer. However, if you experience any symptoms, therapy can provide relief. Pityriasis rosea: Diagnosis and treatment - American Academy of Dermatology Drago F, Ciccarese G, Javor S, Parodi A. Vaccine-induced pityriasis rosea and pityriasis rosea-like eruptions: a review of the literature. N Engl J Med 2020; 383: 26032615. Int J Dermatol. Epub 2022 Jan 31. 2022 Nov 1;43(6):555-558. doi: 10.2500/aap.2022.43.220058. Dermatol Ther. 8 In some cases, antibodies against HHV6/7 as well as viral DNA in plasma and PBMCs were detected. Epub 2021 Nov 2. Dermoscopy of the lesions showing peripheral collarette scaling, blood Cutis. Unable to load your collection due to an error, Unable to load your delegates due to an error. 2022 Nov;36(11):1947-1968. doi: 10.1111/jdv.18294. Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection J Eur Acad Dermatol Venereol. 8600 Rockville Pike Also, topical medication with dermatocorticosteroids and emollients was associated. sharing sensitive information, make sure youre on a federal 2022 Oct 4;15:2117-2127. doi: 10.2147/CCID.S371630. JAAD Int. MeSH 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. *Correspondence: Poonkiat Suchonwanit, poonkiat@hotmail.com, ORCID: Kanchana Leerunyakul orcid.org/0000-0002-0669-5611Kallapan Pakornphadungsit orcid.org/0000-0003-4783-0282Poonkiat Suchonwanit orcid.org/0000-0001-9723-0563, COVID-19 Associated Cutaneous Manifestations and COVID-19 Vaccine Related Skin Reactions, View all It is important for physicians to be aware of this self-limited reaction so they can reassure and appropriately counsel patients that it is safe to receive subsequent vaccine doses despite the cutaneous eruption. eCollection 2022 Jul. (2020) 33:e13878. Pityriasis Rosea | Johns Hopkins Medicine They were found on hands and feet, showing up as red or purple spots caused by bleeding under the skin. eCollection 2022. Would you like email updates of new search results? At first, I thought it could be a fungal infection like ringworm, a common misdiagnosis, says Hartman, but my dermatologist ruled that out when I mentioned the additional spots erupting on my back via our video chat. Dermatology. doi: 10.1111/ijd.15700, 4. PR also tends to occur in patients between the ages of 10 to 35 that are usually otherwise healthy, Lam says. A virus may cause pityriasis rosea, but experts aren't sure. Would you like email updates of new search results? Pityriasis rosealike rashes have been described after H1N1 influenza, HPV, diphtheria, poliomyelitis, smallpox, pneumococcal, hepatitis B and BCG vaccinations. official website and that any information you provide is encrypted The appearance of pityriasis rosea following the first injection of the AstraZeneca vector vaccine suggests a causal connection. Careers. Outcome: Women are 50% more likely to develop pityriasis rosea. J Eur Acad Dermatol Venereol 2016; 30: 544545. However, several adverse effects of COVID-19 vaccination have been identified. If you have a very itchy rash, your healthcare provider may prescribe the following to help relieve your symptoms: There are several over-the-counter products or home remedies that can help stop your rash from itching. 2022 Sep-Oct;40(5):586-590. doi: 10.1016/j.clindermatol.2022.01.002. and transmitted securely. One case of pityriasis rosea is reported in a patient infected with COVID-19, and the most commonly reported features are exanthomatous rash, urticaria, chickenpox like vesicles, petechiae, and acute hemorrhagic edema of infancy. Epub 2022 Jun 19. Global prevalence and clinical manifestations of cutaneous adverse reactions following COVID-19 vaccination: A systematic review and meta-analysis. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of Cond Nast. "Any type of stress on the body can sometimes [cause them, and] any vaccine, not just the COVID one.". Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 Vaccine J Eur Acad Dermatol Venereol. In: Kelly A, Taylor SC, Lim HW, et al., eds. sharing sensitive information, make sure youre on a federal Pityriasis rosea after Moderna mRNA-1273 vaccine: A case series Most of the rare, severe allergic reactions to these vaccines have occurred in people with a history of allergies. Six cases of pityriasis rosea following SARS-CoV-2 vaccination with BNT162b2. The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding author/s. 2021 Aug;185(2):e34. eCollection 2022. Proc (Bayl Univ Med Cent). Involvement of the oral mucosa has also been reported in as many as 50% of all cases (11). 2021 Nov 2;17(11):4097-4098. doi: 10.1080/21645515.2021.1963173. Epub 2021 Aug 7. The etiopathogenesis of PR is still unknown, but is frequently associated with episodes of upper respiratory tract infections. Careers. National Library of Medicine doi: 10.1111/jdv.17342, 5. How long will it take my body to clear the rash? Pityriasis means scaly, and rosea means pink, but the rashes may look red, gray, brown or purple. 2022 Feb 3;9 (2):003164. doi: 10.12890/2022_003164. Copyright 2021 the Author(s). Please enable it to take advantage of the complete set of features! Clinical findings of pityriasis rosealike, Clinical findings of pityriasis rosealike eruption in the patients. The .gov means its official. They develop in a pattern that resembles sagging Christmas tree branches. The most commonly reported features . Bathe or shower in lukewarm water. The clinical and pathologic spectrum of mucocutaneous reactions However, if it does, the symptoms may last for a longer period. official website and that any information you provide is encrypted SARS-CoV-2 spike protein positivity in pityriasis rosea-like and urticaria-like rashes of COVID-19. HHS Vulnerability Disclosure, Help official website and that any information you provide is encrypted With COVID-19 vaccines being authorized for emergency use, monitoring for potential adverse effects (e.g., cutaneous reactions) is necessary. Inverse pityriasis rosea secondary to COVID-19 vaccination. and transmitted securely. Br J Dermatol. Pityriasis rosea is a common condition that causes discolored patches on your skin. We do not endorse non-Cleveland Clinic products or services. Dermoscopy showed dotted and linear vessels forming a network on a yellowish background, with some whitish peripheral scales (Figure 3A). The site is secure. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. They indicate that eight types of rash could be signs of Covid-19, including red toes and fingers, chest eczema and pityriasis rosea (scroll down for the full list). J Invest Dermatol. Healthcare experts believe herpesvirus 6 (HHV-6), HHV-7 and/or HHV-8 cause pityriasis rosea, but there arent any conclusive studies. Med Clin (Barc). Skin lesions appeared in a 49-year-old female 8 days after the first dose of the BNT162b2 mRNA vaccine and in a 53-year-old male 7 days after the second dose of the same vaccine. The .gov means its official. COVID-19-associated pityriasis rosea in children: Case report and literature review. FOIA If you need help purchasing a product directly from Allure, go to our FAQ. Of the 30 cases found, none experienced severe adverse effects and the rash resolved in an average of 5.6 weeks. Epub 2020 Jun 5. J Formos Med Assoc. You may be more likely to develop it if youre: In some cases, people with pityriasis rosea report that they had significant or long-term stress before developing a rash. government site. Cureus. Herald patch in the right hypochondrium followed by typical oval-shaped secondary plaques, Pityriasis rosea lesions on the upper extremities, MeSH Cured meats with nitrates, such as hot dogs. Herein, we are reporting a unique. eCollection 2022 Jul. The authors suggest more research is necessary. How can you tell that I have pityriasis rosea? Under the treatment that was initiated a partial remission of the lesions after 7 days was observed. (b) Patient 1: Closeup of a plaque. User Agreement and Privacy Policy and Cookie Statement and Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. 2022 Jun;7:164-168. doi: 10.1016/j.jdin.2022.01.009. This site needs JavaScript to work properly. A case of Pityriasis rosea is presented in a 66-year-old black male 1 week after administration of the Pfizer-BioNTech COVID-19 vaccine. HHS Vulnerability Disclosure, Help Pityriasis rosea is a common condition that causes discolored patches on your skin. retailers. She diagnosed it as pityriasis rosea, a benign but frustratingly itchy rash that in her words just happens sometimes. Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 vaccine. Epub 2022 Jun 13. Epub 2022 Feb 9. In addition to a corticosteroid cream, New York City-based dermatologist Macrene Alexiades recommends keeping showers short and lukewarm, as "water, sweat, and soap reportedly irritate and inflame the lesions. (No.) As King notes, there have been some reported cases of pityriasis rosea occurring in patients after receiving certain vaccines, like the flu shot. One case of pityriasis rosea is reported in a patient infected with COVID19, and the most commonly reported features are exanthomatous rash, urticaria, chickenpox like vesicles, petechiae, and acute hemorrhagic edema of infancy. The cause of pityriasis rosea is not known, but it is commonly believed to be caused by a virus or bacteria. Oily fish, such as mackerel, salmon or sardines. Advertising on our site helps support our mission. 2022 Nov;36(11):1947-1968. doi: 10.1111/jdv.18294. The .gov means its official. Is there a prescription cream or ointment that you can prescribe? The good news is many of those who develop pityriasis rosea never get it again, says New York City-based dermatologist Hadley King. 18. 2021 Jun 25;118(25):431. doi: 10.3238/arztebl.m2021.0257. doi: 10.1111/bjd.20143. Epub 2022 Jun 26. Pityriasis Rosea-like eruptions following COVID-19 mRNA-1273 vaccination: A case report and literature review. Considering the actual epidemiological context, we performed a real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay from nasal and pharyngeal swabs for coronavirus disease 2019 (COVID-19) to investigate the PR etiology. 2022 Dec;9:127. doi: 10.1016/j.jdin.2022.03.018. Your California Privacy Rights. However, if you scratch your patches, you may break your skin, leading to an infection that can cause pain. There isnt a cure, but it isnt contagious. Rybak-d'Obyrn J, Placek W, Owczarczyk-Saczonek A, Derkaczew M, Joniec E, Hofman R, Stompr M. Clin Cosmet Investig Dermatol. J Eur Acad Dermatol Venereol. Pityriasis rosea: Signs and symptoms - American Academy of Dermatology Those ensuing spots like the circle of dots that erupted on my back a day after the initial raised welt appeared typically resemble a Christmas tree-like formation. Pityriasis rosea Gibert is an erythematous-papulosquamous dermatosis that frequently occurs in young adults. Accessibility "It's usually not from head to toe that's more atypical but there are some people that get it more in the groin area or in the armpit rather than on the trunk predominantly, which is just a variant.". The https:// ensures that you are connecting to the Accessibility (a) Patient 1: Thin, Histopathological findings of pityriasis rosealike, Histopathological findings of pityriasis rosealike eruption in patient 1. Additionally, differences in incidence of this reaction after Pfizer and Moderna vaccination may suggest a differing host immune response incited by these vaccines which warrants further investigation. All rights reserved. Although the exact pathogenesis of PR is unknown, current evidence suggests that an inflammatory reaction due to a viral trigger may lead to the cutaneous manifestations. sharing sensitive information, make sure youre on a federal Epub 2022 Jan 31. Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. FOIA However, in cases of atypical PR, it may present with erythema multiforme-like lesions and purpura (5). 2021 Nov;35(11):e721-e722. Common causes of drug-induced PR-like eruptions include angiotensin-converting enzyme inhibitors, non-steroidal anti-inflammatory drugs, and gold. Case Report: Pityriasis Rosea-Like Eruption Following COVID-19 Vaccination. You also wont have permanent scarring or other damage to your skin. (2021) 60:11501. Unauthorized use of these marks is strictly prohibited. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. -, Johansen M, Chisolm SS, Aspey LD, Brahmbhatt M. Pityriasis rosea in otherwise asymptomatic confirmed COVID-19-positive patients: a report of 2 cases. It's also what's known as a self-limiting rash, Hartman says, in that it can resolve itself on its own without treatment in about six to eight weeks. Pityriasis rosea (PR)-like eruption is a cutaneous complication associated with several medications and vaccinations. See this image and copyright information in PMC. Received: 03 August 2021; Accepted: 17 August 2021; Published: 07 September 2021. 2021 Oct;20(10):3080-3084. doi: 10.1111/jocd.14372. Got an extremely itchy rash that came seemingly out of nowhere? Some studies have identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike proteins on endothelial cells and lymphocytes from PR-like lesions, consistent with direct viral invasion (3, 4). We present the case of a female patient in whom the diagnosis of pityriasis rosea led to the investigation and diagnosis of the SARS-CoV-2 infection. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Epub 2021 Jul 21. Shingles was another fear, as I had chicken pox when I was four, but we ruled that out too: "Shingles is a nerve-mediated process; it tends to be very painful, not so itchy," Lam says. Pityriasis rosea, COVID-19 and vaccination: new keys to understand an old acquaintance.
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